Above the heatwave in 2015 killed more than a 1,000 people in Karachi alone with temperatures approaching 50 deg C (122 deg F).
Heatstroke caused dozens of people to faint as Shaheed Benazirabad district and Larkana as temperatures sizzled at 50.2 degrees Celsius, 123 deg F, respectively, on Monday.
The heatstroke victims were taken to Peoples Medical University Hospital and other medical centres in Nawabshah and its adjoining towns where they received treatment.
The unbearable heat forced people to remain indoors throughout the day.
Roads and markets wore a deserted look and business activities came to a halt.
The worst sufferers of heatstroke were labourers and motorcyclists.
Doctors advised people to drink plenty of water and juices, avoid consuming stale food and keep heads covered with a wet cloth while going out in the sun.
In 2015 killed more than a 1,000 people in Karachi alone with temperatures approaching 50 deg C (122 deg F)